By Eric T. Wong

ISBN-10: 3319305743

ISBN-13: 9783319305745

ISBN-10: 331930576X

ISBN-13: 9783319305769

This concise textual content offers a whole review of alternating electrical fields treatment -- sometimes called tumor treating fields -- for glioblastoma and different forms of good tumor malignancies. Readers are given a primary knowing of this novel anti-cancer remedy modality by means of studying from medical trial information in addition to the actual and cellphone biology results on tumor cells whilst alternating electrical fields are utilized either in vitro and in vivo.

Chapters illustrate the physics in the back of electrical box propagation in house and different media. this can be by means of a assessment of our present knowing of the electrical box results on dividing cells - together with the disruption of cytokinesis, right chromosome segregation and activation at the cellphone floor chaperons that set off immunogenic telephone dying. information from part III trials for the remedy of recurrent and newly clinically determined glioblastomas are incorporated, in addition to a few of the ancillary post hoc analyses that have been played by way of numerous investigators. the rest of the bankruptcy covers different strong tumor malignancies, together with non-small cellphone lung melanoma, pancreatic melanoma and ovarian melanoma, as this remedy modality is being utilized to systemic malignancies.

Alternating electrical Fields remedy in Oncology deals oncologists, neurologists, radiation oncologists, biomedical engineers, mobile biologists and mitosis researchers the basics wanted for scientific practice.

Show description

Read or Download Alternating Electric Fields Therapy in Oncology: A Practical Guide to Clinical Applications of Tumor Treating Fields PDF

Best allied health professions books

New PDF release: Ghrelin

First released in 1943, supplements AND HORMONES is the longest-running serial released through educational Press. within the early days of the Serial, the topics of supplementations and hormones have been relatively particular. The Editorial Board now displays services within the box of hormone motion, diet motion, X-ray crystal constitution, body structure, and enzyme mechanisms.

Becoming an Advanced Healthcare Practitioner by Gillian Brown MSc DipCOT SROT, Susan Esdaile PhD MAPS PDF

This article examines complex perform within the overall healthiness professions and the significance of evidence-based perform, carrying on with specialist improvement, utilizing concept to notify perform, being reflective, moral, and arranged, and proactively making plans a occupation as a complicated practitioner.

Read e-book online Angina and Heart Attack PDF

Hundreds of thousands of individuals in the course of the global be afflicted by heart ailment (CHD). Angina is a symptom of CHD, however the can finally result in a center connect - frequently deadly. Steps will be taken to aid hinder CHD getting worse, hence lowering the chance of a center assault. Many sufferers who've a center assault die sooner than achieving health center.

Download e-book for kindle: The Crosslinguistic Study of Language Acquisition: by Dan Isaac Slobin

See quantity I (0-89859-367-0) for complete description and TOC.

Extra resources for Alternating Electric Fields Therapy in Oncology: A Practical Guide to Clinical Applications of Tumor Treating Fields

Example text

While most external beam radiation therapy uses ionizing radiation with beam-on time of only a few minutes per fraction, the duration of TTFields therapy is orders of magnitude longer. Therefore, on a per unit time basis, TTFields deliver a lower amount of energy to the target tissue than ionizing radiation. Nevertheless, they both damage actively dividing tumor cells and effect downstream anticancer responses. Apart from this similarity, the two types of therapies diverge in their mechanisms of action.

First, Coulomb’s law describes the electric field strength at a test point located at a distance from a charge located in space and time (Fig. 1). Specifically, the field strength decreases in an inverse proportion to the square of the distance or 1 from the charge, where r is the radial distance between the test point and the r2 charge. Fig. 1 Coulomb’s law expresses that the electric field strength drops off with the square of the distance between the charge and at a test point in space. 2 Fundamental Physics of Tumor Treating Fields 17 Fig.

Furthermore the dose dependency of TTFields [7], which relates to the fact that the inhibitory effect of TTFields increases rapidly with 36 C. C. Miranda Fig. 4 DEP forces on a cell during cytokinesis. (A) Close-up of the furrow region and the DEP force component plotted as arrows. (B) The normalized DEP force component for the three stages of cytokinesis. Adapted from Wenger et al. [12]. Fig. 5 Cellular characteristics that influence DEP forces. (A) The peak frequency (kHz) of maximal DEP force component as a function of cell radius (μm) for the three stages of cytokinesis.

Download PDF sample

Alternating Electric Fields Therapy in Oncology: A Practical Guide to Clinical Applications of Tumor Treating Fields by Eric T. Wong


by Michael
4.0

Download e-book for kindle: Alternating Electric Fields Therapy in Oncology: A Practical by Eric T. Wong
Rated 4.52 of 5 – based on 16 votes