By James C. Fishbein

ISBN-10: 0444634061

ISBN-13: 9780444634061

Toxicology is the examine of toxins, and this sequence information the learn of the molecular foundation through which an unlimited array of brokers encountered within the human atmosphere and produced by means of the human physique itself happen themselves as pollutants. now not strictly restricted to documenting those examples, the sequence can be keen on the advanced net of chemical and organic occasions that provide upward thrust to toxin-induced signs and disorder. the hot applied sciences which are being harnessed to investigate and comprehend those occasions can also be reviewed through prime employees within the field.

Volume eight of Advances in Molecular Toxicology maintains within the culture of sampling widely from all corners of this assorted self-discipline.

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Additional resources for Advances in Molecular Toxicology.

Example text

A. , Yessotoxin induces ER-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3, Cell Signal. 26 (2) (2014) 419–432. P. , Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model, Hepatology 45 (2) (2007) 286–296. [140] Y. , Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb, J. Biol. Chem. 282 (49) (2007) 35803–35813. P. , Perk is essential for translational regulation and cell survival during the unfolded protein response, Mol.

M. ), Seafood and Freshwater Toxins: Pharmacology, Physiology and Detection, CRC Press, Boca Rato´n, 2014, pp. 3–38. [5] L. , Simultaneous effect of temperature and irradiance on growth and okadaic acid production from the marine dinoflagellate Prorocentrum belizeanum, Toxins (Basel) 6 (1) (2014) 229–253. J. , Strain dependent production of ciguatoxin precursors (gambiertoxins) by Gambierdiscus toxicus (Dinophyceae) in culture, Toxicon 29 (6) (1991) 761–775. [7] P. , Effects of environmental regimens on the toxin profile of Alexandrium ostenfeldii, Environ.

In Vitro 20 (7) (2006) 1077–1087. S. , Cleavage of tensin during cytoskeleton disruption in YTXinduced apoptosis, Toxicol. In Vitro 21 (1) (2007) 9–15. [112] D. Malagoli, E. Marchesini, E. Ottaviani, Lysosomes as the target of yessotoxin in invertebrate and vertebrate cell lines, Toxicol. Lett. 167 (1) (2006) 75–83. [113] F. P. Rossini, Yessotoxin inhibits the complete degradation of E-cadherin, Toxicology 244 (2–3) (2008) 133–144. 32 Luis M Botana et al. [114] G. P. Rossini, Yessotoxin induces the accumulation of altered E-cadherin dimers that are not part of adhesive structures in intact cells, Toxicology 244 (2–3) (2008) 145–156.

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